IS NESIRITIDE BETTER THAN DIURETIC IN ACUTE DECOMPENSATED HEART FAILURE IN PATIENTS WITH PRESERVED VENTRICULAR FUNCTION AND CHRONIC RENAL INSUFFICIENCY
نویسندگان
چکیده
منابع مشابه
A retrospective characterization of worsening renal function in patients with acute decompensated heart failure receiving nesiritide
UNLABELLED Nesiritide is approved by Food and Drug Administration (FDA) for the treatment of patients with acute decompensated heart failure (ADHF) due its ability to rapidly reduce cardiac filling pressures and improve dyspnea. Numerous studies have shown that renal dysfunction is associated with unfavorable outcomes in patients with heart failure. In addition, there have been reports suggesti...
متن کاملNesiritide in acute decompensated heart failure.
To the Editor: In an editorial accompanying an article by O’Connor et al.1 on the effect of nesiritide in patients with acute decompensated heart failure (July 7 issue), Topol2 describes the meandering path of nesiritide from approval by the Food and Drug Administration (FDA) on the basis of limited data through an ultimately disappointing pivotal trial. This discussion of the unfortunate legac...
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BACKGROUND Renal function is an important prognostic factor for patients with acutely decompensated heart failure (ADHF). We investigated the renal effects of nesiritide as treatment for ADHF. METHODS AND RESULTS Randomized clinical trials comparing nesiritide with either placebo or active control for ADHF were identified by electronic and manual searches and thorough review of US Food and Dr...
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BACKGROUND Loop diuretics are an essential component of therapy for patients with acute decompensated heart failure, but there are few prospective data to guide their use. METHODS In a prospective, double-blind, randomized trial, we assigned 308 patients with acute decompensated heart failure to receive furosemide administered intravenously by means of either a bolus every 12 hours or continu...
متن کاملAssociation between troponin T and impaired left ventricular relaxation in patients with acute decompensated heart failure with preserved systolic function.
AIMS To examine relationships between cardiac troponin T (cTnT) and parameters of left ventricular (LV) structure and function in patients with acute destabilized heart failure (HF) with preserved LV ejection fraction. METHODS AND RESULTS In 44 patients with acute heart failure (HF) with preserved left ventricular (LV) ejection fraction, parameters of LV structure and function were assessed v...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2011
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(11)60221-0